HRID2356644

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID517972

2-Bromo-5-fluorobenzyl bromide

C7H5Br2F

结构：CC1(C)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O

HCID11162285

4-(4,4-Dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile

C13H10F3N3O2

PRODUCTS

生成物

结构：CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1Cc1cc(F)ccc1Br

HCID68677021

未命名化合物

收率 95%

PROCEDURE

实验过程

Compound 15.2 was prepared as described for example 6.2 by reacting compound 1.1 with 2-bromo-5-fluorobenzyl bromide. 4-[3-(2-Bromo-5-fluorobenzyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-trifluoromethylbenzonitrile was obtained in a yield of 95% (molecular weight 483.02 (C20H14BrF4N3O2); retention time Rt=2.10 min. [B]; MS (ESI): 484.26 (MH+)