2,4-Difluoroaniline → HCID 25211836, compound

HRID 2356657Notes

Reaction equation

HRID 2356657 reaction equation
Br[C:2]1[CH:30]=[CH:29][CH:28]=[CH:27][C:3]=1[CH2:4][N:5]1[C:9]([CH3:11])([CH3:10])[C:8](=[O:12])[N:7]([C:13]2[CH:18]=[CH:17][C:16]([O:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[CH:15][CH:14]=2)[C:6]1=[O:26].[F:31][C:32]1[CH:38]=[C:37]([F:39])[CH:36]=[CH:35][C:33]=1[NH2:34]>>[F:31][C:32]1[CH:38]=[C:37]([F:39])[CH:36]=[CH:35][C:33]=1[NH:34][C:2]1[CH:30]=[CH:29][CH:28]=[CH:27][C:3]=1[CH2:4][N:5]1[C:9]([CH3:11])([CH3:10])[C:8](=[O:12])[N:7]([C:13]2[CH:18]=[CH:17][C:16]([O:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[CH:15][CH:14]=2)[C:6]1=[O:26]

Participants

3

Reactant 2

HCID 97092,4-DifluoroanilineHCID 68677976HCID 68677976, compound

Product 1

HCID 25211836HCID 25211836, compound

Procedure

To prepare the compound of example 49, the procedure may be according to process “A”. Analogously to the process described in example 1.2, 49.2 and 2,4-difluoroaniline were reacted. 49: Molecular weight 513.18 (C30H25F2N3O3); retention time Rt=2.41 min. [B]; MS (ESI): 514.23 (MH+).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-57e528c915be47a5b4c2781e5757b0f3
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

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