HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Bromo-3-methyl-2-pyridinyl)butylamine → 3-[4-(5-Bromo-3-methylpyrid-2-yl)-butylamino]benzothiadiazine-1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Bromo-3-methyl-2-pyridinyl)butylamine | HCID 13094272 | — |
| Reactant | 3-Methylthiobenzothiadiazine-1,1-dioxide | HCID 19851874 | — |
| Product | 3-[4-(5-Bromo-3-methylpyrid-2-yl)-butylamino]benzothiadiazine-1,1-dioxide | HCID 19851867 | — |
Reaction Steps
4-(5-Bromo-3-methylpyrid-2-yl)-butylamine (0.73 g) and 3-methylthiobenzothiadiazine-1,1-dioxide (0.68 g) were fused at 130°-140° C. for 3 hours. The product was crystallised from acetonitrile to yield 3-[4-(5-bromo-3-methylpyrid-2-yl)-butylamino]benzothiadiazine-1,1-dioxide m.p. 187°-8° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04640926 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-46d501a6a5134b25aada1ec5c953e339 |
| Source note | uspto-grants-1987_02 |