2,4-Difluoroaniline → HCID 57829298, compound

HRID 2356675Notes

Reaction equation

HRID 2356675 reaction equation
Br[C:2]1[CH:30]=[CH:29][CH:28]=[CH:27][C:3]=1[CH2:4][N:5]1[C:9]([CH3:11])([CH3:10])[C:8](=[O:12])[N:7]([C:13]2[CH:18]=[CH:17][C:16]([S:19]([CH3:21])=[O:20])=[C:15]([C:22]([F:25])([F:24])[F:23])[CH:14]=2)[C:6]1=[O:26].[F:31][C:32]1[CH:38]=[C:37]([F:39])[CH:36]=[CH:35][C:33]=1[NH2:34].FC1C=C([N+]([O-])=O)C=CC=1N=CN(C)C>>[F:31][C:32]1[CH:38]=[C:37]([F:39])[CH:36]=[CH:35][C:33]=1[NH:34][C:2]1[CH:30]=[CH:29][CH:28]=[CH:27][C:3]=1[CH2:4][N:5]1[C:9]([CH3:11])([CH3:10])[C:8](=[O:12])[N:7]([C:13]2[CH:18]=[CH:17][C:16]([S:19]([CH3:21])=[O:20])=[C:15]([C:22]([F:25])([F:24])[F:23])[CH:14]=2)[C:6]1=[O:26]

Participants

4

Reactant 3

HCID 97092,4-DifluoroanilineHCID 57829317HCID 57829317, compoundHCID 68677827HCID 68677827, compound

Product 1

HCID 57829298HCID 57829298, compound

Procedure

The reaction of 114.2 with 2,4-difluoroaniline under conditions as described for the preparation of compound 1 afforded 114. Molecular weight 551.13 (C26H22F5N3O3S); retention time Rt=2.06 min. [B]; MS (ESI): 552.17 (MH+).

Sources & evidence

ORD record
ord-61d62c97dc3343ba80d098274b442027
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

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