HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → Benzonitrile, 2-cyclopropyl-4-(4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Tert-butyl 2-amino-2-methylpropanoate hydrochloride | HCID 12186776 | — |
| Reactant | 1006899-23-5 | HCID 59384227 | — |
| Product | Benzonitrile, 2-cyclopropyl-4-(4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)- | HCID 59384228 | — |
Reaction Steps
Compound 158.1 was prepared by the process as described for 1.1 by reaction of 158.3 with tert-butyl 2-amino-2-methylpropionate hydrochloride and phosgene (solution in toluene). Molecular weight 269.11 (C15H15N3O2); retention time Rt=1.43 min. [B]; MS (ESI): 270.18 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07759366B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-4e8c25158f2b4acca644abe15c3e65aa |
| Source note | uspto-grants-2010_07 |