4-[3-(2-Bromobenzyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-trifluoromethylbenzonitrile → Dimethyl 2-(4-{2-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenylamino}benzyl)malonate

Participants

Role	Name	HCID	Charge
Reactant	4-[3-(2-Bromobenzyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-trifluoromethylbenzonitrile	HCID 58154346	—
Reactant	HCID 68676932	HCID 68676932	—
Product	Dimethyl 2-(4-{2-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenylamino}benzyl)malonate	HCID 57829315	—

Reaction Steps

232 was obtained by reacting compound 232.2 with compound 1.2 under conditions as described for the preparation of compound I. Molecular weight 622.20 (C32H29F3N4O6); retention time Rt=2.21 min. [B]; MS (ESI): 623.21 (MH+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07759366B2
Source dataset	uspto-grants-2010_07
ORD ID	ord-c22dcc885fde4548b2c846084aec091c
Source note	uspto-grants-2010_07