Dichloromethane → HCID 67547600, compound

Participants

Reaction Steps

To a solution of 2-(5-chlorothiophen-2-yl)-5-hydroxy-methyl-4-(3-pyridyl) imidazole (200 mg) in methylene chloride (5 ml) was added thionyl chloride (5 ml), and the mixture was refluxed for one hour. After cooling, the reaction mixture was concentrated under reduced pressure to obtain a crude product of 2-(5-chlorothiophen-2-yl)-5-chloromethyl-4-(3-pyridyl)-imidazole dihydrochloride (260 mg) as yellowish powder.

Provenance & Evidence