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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2356763Generated: October 30, 2026

Hydrochloric Acid → 6-(Dimethylamino)methylnicotinic acid hydrochloride

https://huagongshe.com/reaction/2356763

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethyl 6-(dimethylamino)methylnicotinateHCID 57573795—
Product6-(Dimethylamino)methylnicotinic acid hydrochlorideHCID 67548107—

Reaction Steps

A mixture of methyl 6-(dimethylamino)methylnicotinate (256 mg) and 10N hydrochloric acid was refluxed overnight. After cooling, the reaction mixture was concentrated under reduced pressure to obtain 6-(dimethylamino)methylnicotinic acid hydrochloride (329 mg) as colorless powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07759373B2
Source datasetuspto-grants-2010_07
ORD IDord-6b09a24c70d348d490a60adfd7a79b57
Source noteuspto-grants-2010_07