反应详情

A mixture of methyl 6-(dimethylamino)methylnicotinate (256 mg) and 10N hydrochloric acid was refluxed overnight. After cooling, the reaction mixture was concentrated under reduced pressure to obtain 6-(dimethylamino)methylnicotinic acid hydrochloride (329 mg) as colorless powder.

1. temperaturewas refluxed overnight
2. temperatureAfter cooling
3. concentrationthe reaction mixture was concentrated under reduced pressure