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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2356812Generated: November 1, 2026

3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid → HCID 59385245, compound

https://huagongshe.com/reaction/2356812

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-(methoxycarbonyl)benzeneboronic acidHCID 2782818—
ReactantN-(4-bromo-2-fluorophenyl)-6-fluoro-1,3-benzothiazol-2-amineHCID 7147089—
ProductHCID 59385245HCID 59385245—

Reaction Steps

As shown in Reaction Scheme 8, Intermediate VI-8 (3,3′-difluoro-4′-[(6-fluoro-1,3-benzothiazol-2-yl)amino]biphenyl-4-carboxylic acid) was prepared using a method similar to that employed in the preparation of Intermediate VI-1 using N-(4-bromo-2-fluorophenyl)-6-fluoro-1,3-benzothiazol-2-amine and commercially available [3-fluoro-4-(methoxycarbonyl)phenyl]boronic acid as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07759376B2
Source datasetuspto-grants-2010_07
ORD IDord-ee5c10bd1c114e4b9840cac43cab4a0d
Source noteuspto-grants-2010_07