HCID 68459821, compound → HCID 178472255, compound

Participants

Reaction Conditions

Reaction Steps

250 mg of compound 23 (Example 119) was refluxed in 3 mL of formic acid for 20 min. The mixture was cooled to 25° C. and diluted with 12 mL of distilled water. The resulting precipitate was collected by filtration and dried in a stream of air. It was suspended in 5 mL of chloroform and filtered. The solvent was evaporated from the filtrate at reduced pressure. The residue was stirred with 5 mL of tert-butyl methyl ether for one hour, and then recovered by filtration. The product was obtained as a white powder. Analysis gave 56.84% C, 5.87% H, 13.28% N.

Provenance & Evidence