Methylamine → HCID 10111989, compound

HRID 2356877Notes

Reaction equation

HRID 2356877 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[C:10](=[O:31])[N:11]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([C:27]([O:29]C)=O)[CH:22]=2)[CH:12]=[C:13]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)[CH:14]=1)#[N:2].[CH3:32][NH2:33]>>[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[C:10](=[O:31])[N:11]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([C:27]([NH:33][CH3:32])=[O:29])[CH:22]=2)[CH:12]=[C:13]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)[CH:14]=1)#[N:2]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 10136072HCID 10136072, compound

Product 1

HCID 10111989HCID 10111989, compound

Procedure

3-(2-Cyanophenyl)-5-(2-pyridyl)-1-(3-methoxycarbonylphenyl)-1,2-dihydropyridin-2-one (10 mg) was added to 6 ml of a 40% methanolic solution of methylamine followed by stirring at room temperature for one night. The reaction solution was concentrated in vacuo to give 10 mg of the title compound as a pale yellow solid.

Workup

  1. concentrationThe reaction solution was concentrated in vacuo

Sources & evidence

ORD record
ord-02fc2572e42a48cca7466203605ee13f
Source dataset
uspto-grants-2010_07
Patent number
US07759367B2

Reaction notes

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