HRID2356936

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID138100

Piperidine, 4,4-dimethyl-

C7H15N

结构：CC1(C)C(=O)N(c2ccc(OC(F)(F)F)c(NC(=O)CCl)c2)C(=O)N1Cc1ccncc1

HCID23110283

未命名化合物

PRODUCTS

生成物

结构：CC1(C)CCN(CC(=O)Nc2cc(N3C(=O)N(Cc4ccncc4)C(C)(C)C3=O)ccc2OC(F)(F)F)CC1

HCID11613655

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as described for example 1e using 100 mg N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-chloro-acetamide (raw material, as described above) and 15 mg 4,4-dimethylpiperidine. Yield: 2.5 mg

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1d0b640ef3934af4820e47eb9b1f1b34
来源数据集: uspto-grants-2010_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07759379B2
来源说明: uspto-grants-2010_07

反应 SMILES

[CH3:1][C:2]1([CH3:32])[C:6](=[O:7])[N:5]([C:8]2[CH:9]=[CH:10][C:11]([O:19][C:20]([F:23])([F:22])[F:21])=[C:12]([NH:14][C:15](=[O:18])[CH2:16]Cl)[CH:13]=2)[C:4](=[O:24])[N:3]1[CH2:25][C:26]1[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=1.[CH3:33][C:34]1([CH3:40])[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]1>>[CH3:1][C:2]1([CH3:32])[C:6](=[O:7])[N:5]([C:8]2[CH:9]=[CH:10][C:11]([O:19][C:20]([F:23])([F:22])[F:21])=[C:12]([NH:14][C:15](=[O:18])[CH2:16][N:37]3[CH2:38][CH2:39][C:34]([CH3:40])([CH3:33])[CH2:35][CH2:36]3)[CH:13]=2)[C:4](=[O:24])[N:3]1[CH2:25][C:26]1[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=1