HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-Dimethylpiperidine → N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-(4,4-dimethyl-piperidin-1-yl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-Dimethylpiperidine | HCID 138100 | — |
| Reactant | N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-chloro-acetamide | HCID 23110283 | — |
| Product | N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-(4,4-dimethyl-piperidin-1-yl)-acetamide | HCID 11613655 | — |
Reaction Steps
The title compound was prepared as described for example 1e using 100 mg N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-chloro-acetamide (raw material, as described above) and 15 mg 4,4-dimethylpiperidine. Yield: 2.5 mg
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07759379B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-1d0b640ef3934af4820e47eb9b1f1b34 |
| Source note | uspto-grants-2010_07 |