反应详情

温度

0 °C

25 g (185 mmol) 4-isopropyl-aniline were dissolved in to 260 ml conc. sulfuric acid and treated at −5° C. with 17.9 g nitric acid (65%). After stirring the mixture at 0° C. for 0.5 h, the reaction mixture was poured on ice water and the precipitating product collected via filtration and dried. The resulting 23.8 g product were essentially pure and were used for the subsequent step without further purification.

1. additionthe reaction mixture was poured on ice water
2. filtrationthe precipitating product collected via filtration
3. customdried
4. customwere used for the subsequent step without further purification