HCID 23110280, compound → HCID 23110289, compound

HRID 2356945Notes

Reaction equation

HRID 2356945 reaction equation
[CH2:1]([O:3][CH:4]([O:18][CH2:19][CH3:20])[CH2:5][O:6][C:7]1[CH:12]=[C:11]([N+:13]([O-])=O)[CH:10]=[CH:9][C:8]=1[O:16][CH3:17])[CH3:2]>[Pd].CO>[CH2:19]([O:18][CH:4]([O:3][CH2:1][CH3:2])[CH2:5][O:6][C:7]1[CH:12]=[C:11]([NH2:13])[CH:10]=[CH:9][C:8]=1[O:16][CH3:17])[CH3:20]

Participants

4

Reactant 1

HCID 23110280HCID 23110280, compound

Product 1

HCID 23110289HCID 23110289, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 10.70 g 2-(2,2-diethoxy-ethoxy)-1-methoxy-4-nitro-benzene and 1.20 g of 10% palladium on carbon in 150 ml methanol was stirred for 2 hours under hydrogen atmosphere. The reaction mixture was filtered through a chem elut cartridge and the compound eluted with additional methanol. After contration under reduced pressure the residue was directly subjected to the subsequent reaction without further purification.

Workup

  1. filtrationThe reaction mixture was filtered through a chem elut cartridge
  2. washthe compound eluted with additional methanol
  3. customAfter contration under reduced pressure the residue was directly subjected to the subsequent reaction without further purification

Sources & evidence

ORD record
ord-0846156e2bce4d91b48e3c8e640b7a2e
Source dataset
uspto-grants-2010_07
Patent number
US07759379B2

Reaction notes

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