Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | HCID 23110281 | HCID 23110281 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86617223 | HCID 86617223 | — |
Reaction Steps
410 mg 3-[3-(2,2-Diethoxy-ethoxy)-4-methoxy-phenyl]-5,5-dimethyl-1-quinolin-4-ylmethyl-imidazolidine-2,4-dione were dissolved in 8 ml 1,4-dioxane and 2.05 ml of an aqueous 1 N solution of hydrochloric acid were added. The mixture was stirred for 2 hours at 80° C. Removal of the solvent under reduced pressure yielded a white solid, which was coevaporated twice with toluene. Yield: 340 mg
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07759379B2 |
|---|
| Source dataset | uspto-grants-2010_07 |
|---|
| ORD ID | ord-291898b24d0c46489359c5e3605e9ed9 |
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| Source note | uspto-grants-2010_07 |
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