HCID 21959486, compound → HCID 21959666, compound

Participants

Reaction Steps

A mixture of 240 mg 4-(3,3-dimethyl-6-nitro-2,3-dihydro-indol-1-ylmethyl)-piperidine-1-carboxylic acid tert-butyl ester, 20 mg of 10% palladium on carbon and 5 ml ethanol was stirred for 3 hours under hydrogen atmosphere. The mixture was filtered through a chem elut cartridge and the compound was eluted with ethanol. After concentration under reduced pressure the residue was directly subjected to the subsequent reaction without further purification.

Provenance & Evidence