反应详情

A mixture of about 4.69 g of N-[1-[(octadecyloxy)methyl]-2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]acetamide in about 200 ml of methanol and about 4 ml of about 1N hydrochloric acid was stirred for about 24 hours and the methanol removed under reduced pressure. The residue was dissolved in ethyl acetate, washed with aqueous sodium bicarbonate, dried and the solvent removed, giving about 3.2 g of the desired title compound, mp 82°-85° C.

1. customthe methanol removed under reduced pressure
2. dissolutionThe residue was dissolved in ethyl acetate
3. washwashed with aqueous sodium bicarbonate
4. customdried
5. customthe solvent removed