反应详情

To a refluxing solution of about 35.3 g of hexadecyl iodide in tetrahydrofuran was added a solution of about 37.4 g of bromoanisole and about 4.86 g of magnesium in tetrahydrofuran which had been refluxed for about 2 hours. An about 10 ml portion of about 0.1M lithium cupric chloride was added, the mixture was refluxed about 2 hours and stirred at room temperature for about 16 hours giving about 34 g of the desired reagent.

1. temperaturehad been refluxed for about 2 hours
2. temperaturethe mixture was refluxed about 2 hours