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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2357419Generated: November 2, 2026

Imidazole → HCID 277395, compound

https://huagongshe.com/reaction/2357419

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantSodium BicarbonateHCID 516892—
Reactantα-[(4-Hydroxy-3-methoxyphenyl)methylene]benzeneacetic acidHCID 53411296—
ProductHCID 277395HCID 27739588%

Reaction Steps

A mixture of α-phenyl-4-hydroxy-3-methoxy cinnamic acid (0.0083 mol), NaHCO3 (10%, 5 mL), imidazole (2 mL) and polyethylene glycol (15 mL) were taken in a 250 mL iodine flask fitted with loose funnel at the top. The flask was shaken well and placed inside the microwave oven and irradiated (900 W) for 8 minutes in parts. After completion of reaction, the reaction mixture was worked (yield 88%) as in example I. Spectral data as given in example I.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07759527B2
Source datasetuspto-grants-2010_07
ORD IDord-1d020932b8c64380a0bfd91deba6906f
Source noteuspto-grants-2010_07