Hydrochloric Acid → HCID 10481291, compound

Participants

Reaction Steps

2-(4-dimethylamino-4-phenylcyclohexylidene)-1-[4-(5-methoxy-1H-indol-3-yl)-3,6-dihydro-2H-pyridine-1-yl]-ethanone (252 mg, 0.536 mmole) was suspended in ethanol (20 ml) and 5M isopropanolic hydrochloric acid (0.214 ml, 1.07 mmole) was added. The hydrochloride precipitated out from the clear solution and after 1 hour was isolated as a colourless solid (222 mg, 82%) with an m.p. of 175°-178° C. (Example 28).

Provenance & Evidence