Isopropylamine → HCID 11702889, compound

Participants

Reaction Steps

A mixture of isopropylamine (1.5 mmol), triethylamine (1.5 mmol) and dichloromethane (10 ml) was added to a mixture of 5,7-dichloro-6-(2,3,5-trifluorophenyl)-[1,2,4]-triazolo[1,5-a]pyrimidine (1.5 mmol, obtained from Ex. 3) and dichloromethane (20 ml) under stirring. The reaction mixture was stirred for 16 h. at 20 to 25° C. and washed with 5% hydrochloric acid. The organic layer was separated, dried and filtered. The filtrate was evaporated and the residue was purified by column chromatography to yield 0.42 g of the title compound of mp. 151° C.

Provenance & Evidence