Hydrochloric Acid → HCID 13559271, compound

HRID 235793Notes

Reaction equation

HRID 235793 reaction equation
[C:1]([S:4][CH2:5][C:6]1[NH:7][C:8]([CH3:32])=[C:9]([C:27]([O:29][CH2:30][CH3:31])=[O:28])[CH:10]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[C:23]([F:26])([F:25])[F:24])[C:11]=1C(OCC)=O)(=[O:3])C.Cl>C(O)C>[CH3:32][C:8]1[NH:7][C:6]2[CH2:5][S:4][C:1](=[O:3])[C:11]=2[CH:10]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[C:23]([F:26])([F:25])[F:24])[C:9]=1[C:27]([O:29][CH2:30][CH3:31])=[O:28]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13559270HCID 13559270, compound

Product 1

HCID 13559271HCID 13559271, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10 mmol of diethyl 2 -acetylthiomethyl-6-methyl-4-(2-trifluoromethylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate, dissolved in 40 ml of ethanol, are boiled with 6 ml of saturated ethanolic HCl for 2 hours and the product is precipitated with water and then recrystallized from ethanol.

Workup

  1. customthe product is precipitated with water
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-7d87f6a503a843b39c31b0219576c861
Source dataset
uspto-grants-1987_02
Patent number
US04642310

Reaction notes

Loading…