Allyl bromide → HCID 11645278, compound

HRID 2358084Notes

Reaction equation

HRID 2358084 reaction equation
[CH3:1][C:2]1[C:7]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:12]1[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1.[C:18](=O)([O-])[O-:19].[K+].[K+].C(Br)[CH:25]=[CH2:26]>C(#N)C>[CH3:18][O:19][CH2:25][CH2:26][N:15]1[CH2:16][CH2:17][CH:12]([C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([S:8]([CH3:11])(=[O:10])=[O:9])[C:2]=2[CH3:1])[CH2:13][CH2:14]1

Participants

5

Reactant 3

HCID 7841Allyl bromideHCID 11430Potassium CarbonateHCID 57448039HCID 57448039, compound

Product 1

HCID 11645278HCID 11645278, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Preparation according to Example 1: 4-[2-methyl-3-(methylsulfonyl)phenyl]piperidine (0.01 g), acetonitrile (2 ml), potassium carbonate (0.01) and allylbromide (0.01 g). MS m/z (rel. intensity, 70 eV) 311 (M+, 2), 267 (17), 266 (bp), 129 (8), 70 (10).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-a25e1ef1393b4da9925e5ac69a8848b9
Source dataset
uspto-grants-2010_07
Patent number
US07763639B2

Reaction notes

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