Potassium Carbonate → HCID 67533739, compound

HRID 2358086Notes

Reaction equation

HRID 2358086 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([O:13][C:14]([F:17])([F:16])[F:15])[C:8]=2[OH:18])[CH2:3][CH2:2]1.C(=O)([O-])[O-].[K+].[K+].I[CH2:26][CH2:27][OH:28]>C(#N)C>[OH:28][CH2:27][CH2:26][N:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([O:13][C:14]([F:16])([F:17])[F:15])[C:8]=2[OH:18])[CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 12225IodoethanolHCID 57448054HCID 57448054, compound

Product 1

HCID 67533739HCID 67533739, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Preparation according to Example 1: 2-piperidin-4-yl-6-(trifluoromethoxy)phenol (0.01 g), acetonitrile (2 ml), potassium carbonate (0.01 g) and 2-iodoethanol (0.01 g). MS m/z (relative intensity, 70 eV) 305 (M+, 1), 275 (15), 274 (bp), 117 (5), 70 (20).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-9d26b8c467334444908cedd2f1219039
Source dataset
uspto-grants-2010_07
Patent number
US07763639B2

Reaction notes

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