Iodoethane → HCID 57448047, compound

HRID 2358125Notes

Reaction equation

HRID 2358125 reaction equation
[Cl:1][C:2]1[C:7]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1.I[CH2:19][CH3:20].[BH4-].[Na+]>C(O)C>[Cl:1][C:2]1[C:7]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]1[CH2:13][CH2:14][N:15]([CH2:19][CH3:20])[CH2:16][CH:17]=1

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 4311764Sodium borohydrideHCID 57448059HCID 57448059, compound

Product 1

HCID 57448047HCID 57448047, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation according to preparation 6: 4-[2-chloro-3-(methylsulfonyl)phenyl]-pyridine (1.77 g, 6.6 mmol), 1-iodoethane (5 ml), ethanol (40 ml), sodium borohydride (2.2 g, 58 mmol). Yield: 0.6 g. MS m/z (rel. intensity, 70 eV) 300 (M+, 24), 299 (M+, 71), 298 (33), 284 (bp), 110 (74).

Workup

  1. customPreparation
  2. customaccording to preparation 6

Sources & evidence

ORD record
ord-1eb187fad91a4eba80f5e97d46b6c574
Source dataset
uspto-grants-2010_07
Patent number
US07763639B2

Reaction notes

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