Hydrochloric Acid → HCID 57448055, compound

HRID 2358144Notes

Reaction equation

HRID 2358144 reaction equation
[F:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=2)=[CH:6][CH:5]=[CH:4][C:3]=1[C:14](=[O:16])[CH3:15].Cl>[Pt]=O.CO>[F:1][C:2]1[C:7]([CH:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)=[CH:6][CH:5]=[CH:4][C:3]=1[C:14](=[O:16])[CH3:15]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 57448071HCID 57448071, compound

Product 1

HCID 57448055HCID 57448055, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 887MethanolSolvent

Procedure

Preparation according to preparation 9: 1-(2-fluoro-3-pyridin-4-ylphenyl)ethanone (0.2 g, 0.93 mmol), hydrochloric acid (0.05 ml, conc.) methanol (5 ml), platinum oxide (0.02 g). Yield: 0.2 g. MS m/z (relative intensity, 70 eV) 221 (M+, 25), 220 (37), 178 (96), 149 (41) 101 (20).

Workup

  1. customPreparation
  2. customaccording to preparation 9

Sources & evidence

ORD record
ord-d978eac622574d88a8207fc008342da7
Source dataset
uspto-grants-2010_07
Patent number
US07763639B2

Reaction notes

Loading…