反应详情

is obtained analogously to the procedure described in example 25 a) by reacting 3-chloro-5-trifluoromethyl-1,2-diaminobenzene and 4-methyl-3-thienyl isothiocyanate in anhydrous THF at room temperature for 3 days. The solvent is distilled off and water is added to the residue, and the mixture is then extracted with ethyl acetate, the solvent is again distilled off and the amorphous residue is crystallized under diisopropyl ether. M.p.: >310° C.

1. customis obtained analogously to the procedure
2. customat room temperature
3. customfor 3 days
4. distillationThe solvent is distilled off
5. additionwater is added to the residue
6. extractionthe mixture is then extracted with ethyl acetate
7. distillationthe solvent is again distilled off
8. customthe amorphous residue is crystallized under diisopropyl ether