2,6-Difluorobenzaldehyde → HCID 58000843, compound

HRID 2358266Notes

Reaction equation

HRID 2358266 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[C:9]([C:12]2C=C[N:15]=[C:14](F)[CH:13]=2)=[N:10][OH:11])=[CH:4][CH:3]=1.[F:20][C:21]1[CH:28]=[CH:27][CH:26]=[C:25]([F:29])[C:22]=1[CH:23]=O.[C:30]([O-:33])(=O)[CH3:31].[NH4+:34]>C(O)(=O)C>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:34]=[C:23]([C:22]3[C:21]([F:20])=[CH:28][CH:27]=[CH:26][C:25]=3[F:29])[N:10]([OH:11])[C:9]=2[C:12]2[CH:13]=[CH:14][NH:15][C:30](=[O:33])[CH:31]=2)=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 1362842,6-DifluorobenzaldehydeHCID 517165Ammonium AcetateHCID 136355272HCID 136355272, compound

Product 1

HCID 58000843HCID 58000843, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Using the general procedure found in Example 1 Step C, the intermediate from Example 1 Step B was combined with 2,6-difluorbenzaldehyde, ammonium acetate, and acetic acid: [M+1]+ 444.

Sources & evidence

ORD record
ord-fe703d26c7c441d9aa1850c89b3e4c50
Source dataset
uspto-grants-2010_07
Patent number
US07763634B2

Reaction notes

Loading…