反应详情

Allyl ether 88 (0.5 g, 1.6 mmol) was dissolved in dioxane (10 mL). Triethylamine (0.55 mL, 4 mmol) and formic acid (0.12 mL, 3.2 mmol) were added and the reaction mixture purged with argon. Pd(PPh3)4 (91 mg, 0.08 mmol) was added and the mixture heat to 100 C under a stream of Ar for 1.5 h. A precipitate formed upon cooling. It was isolated by filtration to give 97 as a white solid.

1. customthe reaction mixture purged with argon
2. temperaturethe mixture heat to 100 C under a stream of Ar for 1.5 h
3. customA precipitate formed
4. temperatureupon cooling
5. customIt was isolated by filtration