HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 68455948, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(tert-Butoxycarbonyl)-4-(methanesulfonyloxy)piperidine | HCID 4184869 | — |
| Reactant | HCID 68454676 | HCID 68454676 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 68455948 | HCID 68455948 | 104% |
Reaction Steps
3-(4-tert-Butyl-2-hydroxyphenyl)acrylic acid methyl ester (24.7 mg, 0.105 mmole), 4-methanesulfonyloxypiperidine-1-carboxylic acid tert-butyl ester (58.7 mg, 0.210 mmol), potassium carbonate (43.7 mg, 0.316 mmol) was added in DMF. The reaction mixture was stirred overnight. The reaction mixture was purified according to step 1 of Example 30 to give solid (45.6 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763657B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-478a07692ea442508a553ca79a385c59 |
| Source note | uspto-grants-2010_07 |