HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68456409, compound → HCID 68454731, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68456409 | HCID 68456409 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68454731 | HCID 68454731 | 97.8% |
Reaction Steps
3-[4-tert-Butyl-2-(tetrahydropyran-4-yloxy)phenyl]acrylic acid methyl ester (14.4 mg, 0.045 mmole) and 10 wt. % palladium were added in MeOH. The reaction mixture was stirred overnight under hydrogen atmosphere. The reaction mixture was filtered with celite pad. The filterate was concentrated in vacuo and purified with column chromatography to yield a syrup (14.1 mg, 97.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763657B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-7b0106237eae4d50bc8870f68ba8542a |
| Source note | uspto-grants-2010_07 |