HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → N-(4-aminomethyl-2-vinylphenyl)methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-butyl N-[4-(methanesulfonylamino)-3-vinylbenzyl]carbamate | HCID 68453842 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(4-aminomethyl-2-vinylphenyl)methanesulfonamide | HCID 57665523 | 100% |
Reaction Steps
tert-butyl N-[4-(methanesulfonylamino)-3-vinylbenzyl]carbamate (100 mg, 0.23 mmol) and TFA (0.4 ml) were added in methylene chloride (2 mL). The reaction mixture was stirred overnight at room temperature. The reaction mixture was concentrated in vacuo to yield title compound (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763657B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-4526187acada425ca43e0ba34d9fc053 |
| Source note | uspto-grants-2010_07 |