HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(4-tert-butyl-phenyl)-N-(4-methanesulfonylamino-3-vinyl-benzyl)-2-phenyl-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(4-aminomethyl-2-vinylphenyl)methanesulfonamide | HCID 57665523 | — |
| Reactant | 3-(4-tert-Butyl-phenyl)-2-phenyl-acrylic Acid | HCID 68453697 | — |
| Product | 3-(4-tert-butyl-phenyl)-N-(4-methanesulfonylamino-3-vinyl-benzyl)-2-phenyl-acrylamide | HCID 68456138 | 46% |
Reaction Steps
4-Methanesulfonylamino-3-vinyl-benzylamine and HCl salt (153 mg, 0.582 mmol) were reacted with 3-(4-tert-butyl-phenyl)-2-phenyl-acrylic acid (160.4 mg) to give 3-(4-tert-butyl-phenyl)-N-(4-methanesulfonylamino-3-vinyl-benzyl)-2-phenyl-acrylamide (130.8 mg, 46%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763657B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-2cbc6ed1ff7e49769577e7790ccf153a |
| Source note | uspto-grants-2010_07 |