HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 68456794, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 76587256 | HCID 76587256 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68456794 | HCID 68456794 | 193.3% |
Reaction Steps
[1-(4-Methanesulfonylamino-3-phenylethynylphenyl)ethyl]carbamic acid tert-butyl ester (300 mg, 0.724 mmol) and trifluoroacetic acid (279 μl, 3.619 mmol, 3 eq) were added in methylene chloride. The reaction mixture was stirred for 24 hrs. A reaction solvent was removed in vacuo to yield 1-(4-methanesulfonylamino-3-phenylethynylphenyl)ethylamine (440.1 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763657B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-c91317e1a42b47cda8bdcbaecd265f2d |
| Source note | uspto-grants-2010_07 |