2,5-Hexanedione → HCID 59390004, compound

HRID 2358558Notes

Reaction equation

HRID 2358558 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([NH2:8])[CH:5]=[CH:4][CH:3]=1.[CH3:9][C:10](=O)[CH2:11][CH2:12][C:13](=O)[CH3:14]>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]([N:8]2[C:13]([CH3:14])=[CH:12][CH:11]=[C:10]2[CH3:9])[N:7]=1

Participants

3

Reactant 2

HCID 80352,5-HexanedioneHCID 2062462-Amino-6-chloropyridine

Product 1

HCID 59390004HCID 59390004, compoundYield 55%

Procedure

The product from Example 12a (20 g, 156 mmol) was treated with hexane-2,5-dione (18.3 mL, 156 mmol) for 2 h following the procedure from Example 2a giving the title compound (17.7 g 55%).

Sources & evidence

ORD record
ord-b642e9561bf0414c9d40b9d0d5b7087f
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

Loading…