HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylphenol → HCID 68461887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylphenol | HCID 7264 | — |
| Reactant | 5-Chloro-2-methyl-1,8-naphthyridine | HCID 12266372 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68461887 | HCID 68461887 | — |
Reaction Steps
The product from Example 1d (893 mg, 5 mmol) and 2-Amino-4-methyl-phenol (616 mg, 5 mmol) in ethanol (20 mL) were refluxed for 4 hours. The mixture was cooled to room temperature and evaporated. The residue was triturated with hexane/ethyl acetate (3:1) to give the title compound in quantitative yield as the hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763731B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-fe08ef76e90f4c1991afd4808eac834b |
| Source note | uspto-grants-2010_07 |