Phosphorus oxychloride → HCID 13392298, compound

HRID 235874Notes

Reaction equation

HRID 235874 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:22]=[CH:23][C:24]=1[Cl:25])[C:5]([NH:7][CH:8]([C:15]([C:17]1[CH:21]=[CH:20][O:19][CH:18]=1)=[O:16])[CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=O.P(Cl)(Cl)(Cl)=O>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:3]=[C:4]([C:5]2[O:16][C:15]([C:17]3[CH:21]=[CH:20][O:19][CH:18]=3)=[C:8]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[N:7]=2)[CH:22]=[CH:23][C:24]=1[Cl:25]

Participants

4

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 13773143HCID 13773143, compound

Product 1

HCID 13392298HCID 13392298, compoundYield 46.6%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

10.0 g of ethyl 3-(3,4-dichlorobenzoylamino)-3-(3-furylcarbonyl)propionate, 50 ml of chloroform and 20.0 g of phosphorus oxychloride are treated in the same manner as described in Example 1. 4.44 g of ethyl 2-[2-(3,4-dichlorophenyl)-5-(3-furyl)-4-oxazolyl]acetate are thereby obtained. Yield: 46.5%

Sources & evidence

ORD record
ord-a001c1fd8c984885bd66cd05b62037af
Source dataset
uspto-grants-1987_02
Patent number
US04642313

Reaction notes

Loading…