Ammonium Chloride → 4-(3-Amino-5-chloro-phenoxymethyl)-N-methyl-benzamide

HRID 2358784Notes

Reaction equation

HRID 2358784 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:17]=[C:18]([N+:20]([O-])=O)[CH:19]=1)[O:5][CH2:6][C:7]1[CH:16]=[CH:15][C:10]([C:11]([NH:13][CH3:14])=[O:12])=[CH:9][CH:8]=1.[NH4+].[Cl-]>[Fe]>[NH2:20][C:18]1[CH:17]=[C:4]([CH:3]=[C:2]([Cl:1])[CH:19]=1)[O:5][CH2:6][C:7]1[CH:16]=[CH:15][C:10]([C:11]([NH:13][CH3:14])=[O:12])=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 684568784-(3-Chloro-5-nitro-phenoxymethyl)-N-methyl-benzamide

Product 1

HCID 684587354-(3-Amino-5-chloro-phenoxymethyl)-N-methyl-benzamide

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

The product from Example 195c was reduced with Fe and NH4Cl following the procedure from Example 237E to give the title compound.

Sources & evidence

ORD record
ord-09d64b6231614ff88b35fb25f072662e
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

Loading…