HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2358799Generated: October 30, 2026
5-Chloro-2-methyl-1,8-naphthyridine → HCID 68460633, compound
https://huagongshe.com/reaction/2358799
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 5-Chloro-2-methyl-1,8-naphthyridine | HCID 12266372 | — |
| Reactant | HCID 26189305 | HCID 26189305 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68460633 | HCID 68460633 | — |
Reaction Steps
The product from Example 1d (175 mg, 0.979 mmol) and the product from Example 208b (272 mg, 0.979 mmol) were dissolved in 2 mL of abs EtOH and heated to 80° C. for 16 hrs. At this time the reaction mixture was cooled and solvent removed yielding the title compound as a brown foam that was taken forward without purification (410 mg, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07763731B2 |
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| Source dataset | uspto-grants-2010_07 |
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| ORD ID | ord-3b75b1169f284326974fb7645d96f273 |
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| Source note | uspto-grants-2010_07 |
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