Benzoyl chloride → HCID 13773123, compound

HRID 235892Notes

Reaction equation

Cl.[O:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([CH2:9][NH2:10])=[O:8].C(=O)(O)[O-].[Na+].[C:16](Cl)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:16]([NH:10][CH2:9][C:7]([C:3]1[O:2][CH:6]=[CH:5][CH:4]=1)=[O:8])(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

Reactant 3

HCID 7412Benzoyl chloride

HCID 516892Sodium Bicarbonate

HCID 132261382-Amino-1-(furan-2-yl)ethan-1-one--hydrogen chloride (1/1)

Product 1

HCID 13773123HCID 13773123, compoundYield 83.3%

Procedure

3.4 g of (2-furylcarbonyl)methylamine hydrochloride, 4.4 g of sodium bicarbonate and 3.3 g of benzoyl chloride are treated in the same manner as described in Preparation 1-(1). 4.0 g of N-benzoyl-(2-furylcarbonyl)methylamine are thereby obtained. Yield: 83.3%

Workup

customas described in Preparation 1-(1)

Sources & evidence

ORD record: ord-c6fb2ee2f7564d06a1f0aa628a5cdb0e
Source dataset: uspto-grants-1987_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04642313

Reaction notes

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