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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 235894Generated: October 31, 2026

4-Fluorobenzoyl chloride → 4-Fluoro-N-[2-(furan-2-yl)-2-oxoethyl]benzamide

https://huagongshe.com/reaction/235894

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoyl chlorideHCID 67879—
ReactantSodium BicarbonateHCID 516892—
Reactant2-Amino-1-(furan-2-yl)ethan-1-one--hydrogen chloride (1/1)HCID 13226138—
Product4-Fluoro-N-[2-(furan-2-yl)-2-oxoethyl]benzamideHCID 1347073367%

Reaction Steps

23.4 g of (2-furylcarbonyl)methylamine hydrochloride, 29.3 g of sodium bicarbonate and 23.0 g of 4-fluorobenzoyl chloride are treated in the same manner as described in Preparation 1-(1). 24.0 g of N-(4-fluorobenzoyl)-(2-furylcarbonyl)methylamine are thereby obtained. Yield: 66.8%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04642313
Source datasetuspto-grants-1987_02
ORD IDord-be7d3b4d25604a049b6409e91e38003e
Source noteuspto-grants-1987_02