HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyryl chloride → N-[2-(Furan-2-yl)-2-oxoethyl]-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyryl chloride | HCID 62325 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-Amino-1-(furan-2-yl)ethan-1-one--hydrogen chloride (1/1) | HCID 13226138 | — |
| Product | N-[2-(Furan-2-yl)-2-oxoethyl]-2-methylpropanamide | HCID 13773127 | 67.3% |
Reaction Steps
16.0 g of (2-furylcarbonyl)methylamine hydrochloride, 20.5 g of sodium bicarbonate and 11.4 g of isobutyryl chloride are treated in the same manner as described in Preparation 1-(1). 13.0 g of N-isobutyryl-(2-furylcarbonyl)methylamine are thereby obtained. Yield: 67.0%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04642313 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-2d53a3c51f7145179e7411d1a9b956a7 |
| Source note | uspto-grants-1987_02 |