Hydrazine hydrate (1:1) → HCID 178477882, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1-(5-chloro-2-thienyl)-3-(dimethylamino)-2-(2-chloropyridin-4-yl)prop-2-en-1-one (10 mmol), hydrazine hydrate (20 mmol) in 90 mL ethanol was stirred at 80° C. for 1.5 h. The solvent was evaporated under reduced pressure to afford 3 g 2-chloro-4-[3-(5-chloro-2-thienyl)-1H-pyrazol-4-yl]pyridine (95% yield).

Provenance & Evidence