HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanecarbonyl chloride → N-[2-(Furan-2-yl)-2-oxoethyl]cyclohexanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanecarbonyl chloride | HCID 75938 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-Amino-1-(furan-2-yl)ethan-1-one--hydrogen chloride (1/1) | HCID 13226138 | — |
| Product | N-[2-(Furan-2-yl)-2-oxoethyl]cyclohexanecarboxamide | HCID 13773128 | 91.5% |
Reaction Steps
5.0 g of (2-furylcarbonyl)methylamine hydrochloride, 7.6 g of sodium bicarbonate and 4.8 g of cyclohexylcarbonyl chloride are treated in the same manner as described in Preparation 1-(1). 6.5 g of N-cyclohexylcarbonyl-(2-furylcarbonyl)methylamine are thereby obtained. Yield: 91.5%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04642313 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-f2c5f92bd3a04fc38d078a79145b0a51 |
| Source note | uspto-grants-1987_02 |