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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2359348Generated: October 31, 2026

(-)-3-Hydroxytetrahydrofuran → HCID 58495746, compound

https://huagongshe.com/reaction/2359348

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(-)-3-HydroxytetrahydrofuranHCID 641512—
ReactantHCID 58495736HCID 58495736—
ProductHCID 58495746HCID 5849574679%

Reaction Steps

Using benzyl 4-(2-{[(4-methylphenyl)sulfony]oxy}ethoxy)piperidine-1-carboxylate (4.00 g, 9.23 mmol) produced in Reference Example 1 (1c) and (3R)-tetrahydrofuran-3-ol (1.05 g, 12.0 mmol), the desired title compound (1.56 g, yield 79%) was obtained by the same method as in Reference Examples 1 (1d) and 1 (1e).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08685981B2
Source datasetuspto-grants-2014_04
ORD IDord-5d5da2b532ba49c9998b8c5e3bc36ed6
Source noteuspto-grants-2014_04