HuagongsheHuagongshe Chemistry Print Report · For research reference only
(-)-3-Hydroxytetrahydrofuran → HCID 58495746, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (-)-3-Hydroxytetrahydrofuran | HCID 641512 | — |
| Reactant | HCID 58495736 | HCID 58495736 | — |
| Product | HCID 58495746 | HCID 58495746 | 79% |
Reaction Steps
Using benzyl 4-(2-{[(4-methylphenyl)sulfony]oxy}ethoxy)piperidine-1-carboxylate (4.00 g, 9.23 mmol) produced in Reference Example 1 (1c) and (3R)-tetrahydrofuran-3-ol (1.05 g, 12.0 mmol), the desired title compound (1.56 g, yield 79%) was obtained by the same method as in Reference Examples 1 (1d) and 1 (1e).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08685981B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-5d5da2b532ba49c9998b8c5e3bc36ed6 |
| Source note | uspto-grants-2014_04 |