Thionyl Chloride → HCID 58154605, compound

Participants

Reaction Steps

A solution of 6-(3-(trifluoromethoxy)phenyl)pyrido[3,2-d]pyrimidin-4-ol (1.2 g, 3.9 mmol) in SOCl2 (10 mL) was refluxed for 2 hours. The reaction was concentrated under reduce pressure, and the residue was chased with toluene (10 mL) to obtain 4-chloro-6-(3-(trifluoromethoxy)phenyl)pyrido[3,2-d]pyrimidine as a brown solid. Used as is without further purification.

Provenance & Evidence