Hydrochloric Acid → HCID 178515903, compound

HRID 235947Notes

Reaction equation

HRID 235947 reaction equation
Br[C:2]1[N:3]=[C:4]([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[NH:5][CH:6]=1.[ClH:14]>>[Cl:14][C:2]1[N:3]=[C:4]([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[NH:5][CH:6]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178515896HCID 178515896, compound

Product 1

HCID 178515903HCID 178515903, compoundYield 49%

Procedure

Into a glass, thick-walled tube was placed 11 (1.5 g, 0.0063 mol) and 12N HCl (100 ml). The contents were frozen and the tube sealed and placed in a bath at 120° C. After 5 days, the contents in the tube were cooled, filtered, the solid stirred overnight with saturated NaHCO3 solution and filtered to yield 0.59 g (49%) of 13.

Workup

  1. temperatureThe contents were frozen
  2. customthe tube sealed
  3. customplaced in a bath at 120° C
  4. temperaturethe contents in the tube were cooled
  5. filtrationfiltered
  6. filtrationfiltered

Sources & evidence

ORD record
ord-6e63ee14fd7d4498941e5029c7fb9b3a
Source dataset
uspto-grants-1987_02
Patent number
US04642311

Reaction notes

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