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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2359867Generated: November 1, 2026

HCID 18349590, compound → HCID 16045947, compound

https://huagongshe.com/reaction/2359867

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18349590HCID 18349590—
ReactantPotassium tert-butoxideHCID 23665647—
ReactantHCID 86098791HCID 86098791—
ProductHCID 16045947HCID 16045947—

Reaction Steps

The title compound was synthesized according to EXAMPLE 11 from 3-amino-2-pyridine carboxaldehyde trifluoroacetate (in turn synthesized from (2-formylpyridin-3-yl)carbamate tert-butyl ester by treatment with trifluoroacetic acid) and 3-(2-methoxyphenyl)propionitrile. One equivalent of potassium tert-butylate was additionally used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686002B2
Source datasetuspto-grants-2014_04
ORD IDord-b2236520e32e4b318970e2b86699e7a1
Source noteuspto-grants-2014_04